000 03175cam a22003737a 4500
001 17985330
003 IIITD
005 20171122020003.0
008 131231s2013 enka b 001 0 eng d
010 _a 2013958453
016 7 _a016499393
_2Uk
020 _a9781447153030
035 _a(OCoLC)ocn857973608
040 _aBTCTA
_beng
_cBTCTA
_dUKMGB
_dYDXCP
_dCDX
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_dDGU
_dDLC
042 _alccopycat
082 _a572.8
_bSAI-I
100 1 _aSaitou, Naruya
245 1 0 _aIntroduction to evolutionary genomics
_cNaruya Saitou
260 _aNew York :
_bSpringer,
_c©2013.
300 _axxiii, 461 p. :
_bill. ;
_c24cm.
490 1 _aComputational biology,
_x1568-2684 ;
_v17
504 _aIncludes bibliographical references and index.
505 0 _aPart I : Basic processes of genome evolution -- Basic metabolism surrounding DNAs -- Mutation -- Phylogeny -- Neutral evolution -- Natural selection -- Part II : Evolving genomes -- A brief history of life -- Prokaryote genomes -- Eukaryote genomes -- Vertebrate genomes -- Human genome -- Part III : Methods for evolutionary genomics -- Genome sequencing -- Omic data collection -- Databases -- Sequence homology handling -- Evolutionary distances -- Tree and network building -- Population genomics.
520 _aEvolutionary genomics is a new discipline that bridges the fields of molecular evolution, bioinformatics and genomics in order to provide a unique perspective on the history of life. This easy-to-follow textbook is the first of its kind to explain the fundamentals of evolutionary genomics. The comprehensive coverage includes concise descriptions of a variety of genome organizations, a thorough discussion of the methods used, and a detailed review of genome sequence processing procedures. The opening chapters also provide the necessary basics for readers unfamiliar with evolutionary studies. Topics and features: Introduces the basics of molecular biology, DNA replication, mutation, phylogeny, neutral evolution, and natural selection Presents a brief evolutionary history of life from the primordial seas to the emergence of modern humans Describes the genomes of prokaryotes, eukaryotes, vertebrates, and humans Reviews methods for genome sequencing, phenotype data collection, homology searches and analysis, and phylogenetic tree and network building. Discusses databases of genome sequences and related information, evolutionary distances, and population genomics Provides supplementary material at the website http://www.saitou-naruya-laboratory.org/Evolutionary_Genomics/ This essential text/reference provides an easy-to-read introduction to the field for undergraduate and graduate students, post-doctoral fellows, and established researchers from both computer science and the biological sciences.--
650 0 _aEvolutionary genetics
_xStatistical methods.
650 0 _aGenomics.
650 0 _aGene mapping.
650 0 _aEvolution (Biology)
830 0 _aComputational biology ;
_v17.
906 _a7
_bcbc
_ccopycat
_d2
_encip
_f20
_gy-gencatlg
942 _2ddc
_cBK
_01
999 _c11048
_d11048