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020 _a9783030603274
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024 7 _a10.1007/978-3-030-60327-4
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082 0 4 _a570.285
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082 0 4 _a570.113
_223
245 1 0 _aComputational Methods in Systems Biology
_h[electronic resource] :
_b18th International Conference, CMSB 2020, Konstanz, Germany, September 23–25, 2020, Proceedings /
_cedited by Alessandro Abate, Tatjana Petrov, Verena Wolf.
250 _a1st ed. 2020.
264 1 _aCham :
_bSpringer International Publishing :
_bImprint: Springer,
_c2020.
300 _aXIX, 387 p. 208 illus., 57 illus. in color.
_bonline resource.
336 _atext
_btxt
_2rdacontent
337 _acomputer
_bc
_2rdamedia
338 _aonline resource
_bcr
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347 _atext file
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490 1 _aLecture Notes in Bioinformatics,
_x2366-6331 ;
_v12314
505 0 _aModelling and Analysis -- Rate Equations For Graphs -- Stationary Distributions and Metastable Behaviour for Self-Regulating Proteins with General Lifetime Distributions -- Accelerating Reactions at the DNA Can Slow Down Transient Gene Expression -- Graphical Conditions for Rate Independence in Chemical Reaction Networks -- Interval Constraint Satisfaction and Optimization for Biological Homeostasis and Multistationarity -- Growth Dependent Computation of Chokepoints in Metabolic Networks -- On the Complexity of Quadratization for Polynomial Differential Equations -- Comparing Probabilistic and Logic Programming Approaches to Predict the Effects of Enzymes in a Neurogenerative Disease Model -- Boolean Networks -- Control Strategy Identification via Trap Spaces in Boolean Networks -- Qualitative Analysis of Mammalian Circadian Oscillations: Cycle Dynamics and Robustness -- Synthesis and Simulation of Ensembles of Boolean Networks for Cell Fate Decision -- Classifier Construction in Boolean Networks Using Algebraic Methods -- Sequential Temporary and Permanent Control of Boolean Networks -- Inference and Identification -- ABC(SMC)^2: Simultaneous Inference and Model Checking of Chemical Reaction Networks -- Parameter Synthesis for Hybrid Systems from Hybrid CTL Specifications -- Core Models of Receptor Reactions Evaluate Basic Pathway Designs Enabling Heterogeneous Commitments to Apoptosis -- Drawing the Line: Basin Boundaries in Safe Petri Nets -- Tools -- ModRev - Model Revision Tool for Boolean Logical Models of Biological Regulatory Networks -- fnyzer: a Python Package for the Analysis of Flexible Nets -- eBCSgen: A Software Tool for Biochemical Space Language -- What is a Cell Cycle Checkpoint ? The TotemBioNet Answer -- Kaemika App, Integrating Protocols and Chemical Simulation -- Tutorials -- Tutorial: The CoLoMoTo Interactive Notebook, Accessible and Reproducible Computational Analyses for Qualitative Biological Networks -- Integrating Experimental Pharmacology and Systems Biology for GPCR Drug Discovery.
520 _aThis book constitutes the refereed proceedings of the 18th International Conference on Computational Methods in Systems Biology, CMSB 2020, held in Konstanz, Germany, in September 2020.* The 17 full papers and 5 tool papers were carefully reviewed and selected from 30 submissions. In addition 3 abstracts of invited talks and 2 tutorials have been included in this volume. Topics of interest include formalisms for modeling biological processes; models and their biological applications; frameworks for model verification, validation, analysis, and simulation of biological systems; high-performance computational systems biology and parallel implementations; model inference from experimental data; model integration from biological databases; multi-scale modeling and analysis methods; computational approaches for synthetic biology; and case studies in systems and synthetic biology. * The conference was held virtually due to the COVID-19 pandemic.
650 0 _aBioinformatics.
650 0 _aComputer science
_xMathematics.
650 0 _aComputer networks .
650 0 _aComputer science.
650 0 _aArtificial intelligence.
650 0 _aSoftware engineering.
650 1 4 _aComputational and Systems Biology.
650 2 4 _aMathematics of Computing.
650 2 4 _aComputer Communication Networks.
650 2 4 _aTheory of Computation.
650 2 4 _aArtificial Intelligence.
650 2 4 _aSoftware Engineering.
700 1 _aAbate, Alessandro.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aPetrov, Tatjana.
_eeditor.
_4edt
_4http://id.loc.gov/vocabulary/relators/edt
700 1 _aWolf, Verena.
_eeditor.
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710 2 _aSpringerLink (Online service)
773 0 _tSpringer Nature eBook
776 0 8 _iPrinted edition:
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776 0 8 _iPrinted edition:
_z9783030603281
830 0 _aLecture Notes in Bioinformatics,
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_v12314
856 4 0 _uhttps://doi.org/10.1007/978-3-030-60327-4
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